Top Purity Pharmaceutical Raw Material Powder CAS 59122-46-2 Misoprostol
Product Name: Misoprostol
Synonyms: CYTOTEC; SC-29333
CAS:Â Â Â Â 59122-46-2
MF:Â Â Â Â C22H38O5
MW:Â Â Â Â 382.54
mp:    261-263°C
storage temp:     20°C
appearance:Â Â White Solid
Description:
Misoprostol is a medication used to start labor, induce abortions, prevent and treat stomach ulcers, and treat postpartum bleeding due to insufficient contraction of the uterus. For abortions it is used with mifepristone . It is a synthetic prostaglandin E1 (PGE1).
Common side effects include diarrhea and abdominal pain. It is pregnancy category XÂ meaning that it is known to result in negative fetal outcomes if taken during pregnancy. Uterine rupture may occur.
Usage:
Misoprostol acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications. Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of gastric ulceration.
Misoprostol has other protective actions, but is only clinically effective at doses high enough to reduce gastric acid secretion. For instance, at lower doses, misoprostol may stimulate increased secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood flow, thereby increasing mucosal integrity. However, these effects are not pronounced enough to warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid suppression.
However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as effective as misoprostol,but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily doses are the main issues impairing compliance with therapy.
Some of my customers feedback:
1. I have received my products, you packing is do discreet and perfect, it really amazed me. I will order more from you as soon as possible. Thanks a lot.
--------------Robet--Australia
2. I have cooperated with you for many times, your product quality is so great, that is why I still buy the products from you. Thank you
-----------Richard---American
3 Hi mate, your best price and high purity product is so competitive in my country, this let me make much profit, my customers are really like it. Cooperate with you is so wonderful! Thak you
--------------Johnson---Canada
Our advantages:
1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) Â We have our own agent/remailer/distributor who can help us ship our products very fast and safe,Â
and we have stock in there for transferring.
3,We have clients throughout the world.
 1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) Â High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.
Product Name: Misoprostol
Synonyms: CYTOTEC; SC-29333
CAS:Â Â Â Â 59122-46-2
MF:Â Â Â Â C22H38O5
MW:Â Â Â Â 382.54
mp:    261-263°C
storage temp:     20°C
appearance:Â Â White Solid
Description:
Misoprostol is a medication used to start labor, induce abortions, prevent and treat stomach ulcers, and treat postpartum bleeding due to insufficient contraction of the uterus. For abortions it is used with mifepristone . It is a synthetic prostaglandin E1 (PGE1).
Common side effects include diarrhea and abdominal pain. It is pregnancy category XÂ meaning that it is known to result in negative fetal outcomes if taken during pregnancy. Uterine rupture may occur.
Usage:
Misoprostol acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications. Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of gastric ulceration.
Misoprostol has other protective actions, but is only clinically effective at doses high enough to reduce gastric acid secretion. For instance, at lower doses, misoprostol may stimulate increased secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood flow, thereby increasing mucosal integrity. However, these effects are not pronounced enough to warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid suppression.
However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as effective as misoprostol,but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily doses are the main issues impairing compliance with therapy.
Some of my customers feedback:
1. I have received my products, you packing is do discreet and perfect, it really amazed me. I will order more from you as soon as possible. Thanks a lot.
--------------Robet--Australia
2. I have cooperated with you for many times, your product quality is so great, that is why I still buy the products from you. Thank you
-----------Richard---American
3 Hi mate, your best price and high purity product is so competitive in my country, this let me make much profit, my customers are really like it. Cooperate with you is so wonderful! Thak you
--------------Johnson---Canada
Our advantages:
1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) Â We have our own agent/remailer/distributor who can help us ship our products very fast and safe,Â
and we have stock in there for transferring.
3,We have clients throughout the world.
 1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) Â High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.