Drugs that can cause miscarriage in pregnant sows

Dr. Yang: Hello!

I am a rural veterinarian. I often encounter sterilized gilts reared by farmers. I often abandon the treatment because of concerns that the use of the wrong medicine may lead to miscarriage of sows. As a result, the timing of diagnosis and treatment is lost, causing unnecessary economic losses to farmers. . Trouble you to help me introduce some clinical contraindications for pregnant sows! Thank you!

Reader: Hello!

Care should be taken with pregnant sows. Careless attention can lead to miscarriage of sows. Sows are susceptible to miscarriage 9-13 days after mating and 21 days before delivery. Pregnant sows only need to consider the prevention of miscarriage when they are sick. Within 45 days of breeding, embryo implantation period, this time easily lead to miscarriage, so pay special attention to this 45-day drug contraindications. The following are the banned drugs for pregnant animals that I have summarized from clinical practice and theoretical books:

Furosemide (furosemide) is banned in animals during the first trimester of pregnancy (within 45 days) because diuretic drugs cause dehydration of the uterus and cause embryonic detachment. Antihypertensive drugs, such as reserpine, placenta penetrability is very strong, easily lead to miscarriage, pregnant animals banned.

Antipyretic analgesics are essential in the veterinary world, but phenylbutazone (buhexione) is the most toxic and can easily cause gastrointestinal reactions, liver and kidney damage, sodium and water retention, and can easily cause miscarriage, so it is prohibited. Secondly, sodium salicylate and aspirin have anticoagulant effects and are prone to induce abortion. Therefore, pregnant animals are prohibited. Other antipyretic drugs can be used in the amount, and it is not easy to increase the dosage arbitrarily.

Antibiotics, such as streptomycin, are highly toxic to the fetus and can easily lead to debilitating and avoid use. Tilmicosin injection, placenta penetration is very strong, easily lead to miscarriage, pregnant animals banned.

Hormonal drugs, such as testosterone propionate, diethylstilbestrol, prostaglandins (PG), dexamethasone, can easily lead to miscarriage, and pregnant animals are prohibited. Hydrocortisone can be used as appropriate.

Cholinergic drugs, such as carbamylcholine, pilocarpine, trichlorfon, etc., can easily lead to enhanced uterine smooth muscle excitability, and banned pregnant animals.

Uterine contractions such as oxytocin and pituitrin.

Safflower, Angelica, etc., have the effect of excitement of the uterus and can easily cause miscarriage and premature birth. Rhubarb, Glauber's salt, and Croton can cause intense contraction of the uterus by irritating the intestines, leading to miscarriage and premature birth. In addition, the blood-breaking drugs, diarrhea, under the attack of water-based drugs, Tongqiao take medicine, although clinically not commonly used, but it should not be used.

Overall, animal health taboos are much more concise than humans. For example, pregnant women taking tetracyclines can cause neonatal teeth to become yellow-toothed, but they can't be considered for pigs. Even teratogenic drugs do not matter. On the other hand, animal health care is far more complex than humans. Some abortions are caused by drugs and some are caused by diseases. Therefore, first of all, it is necessary to clarify the contraindications for the use of pregnant animals in order to clarify the responsibilities and be aware of the facts. For example, if the sow has a fever, you have a miscarriage. If it is not a needle problem, you can consider reproductive disorders. In rural areas, there are many farmers who are worried about the sickness of pregnant sows. Pregnant sows are sick and use drugs to prevent diseases, reduce miscarriage, and increase production efficiency.

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