Animal surgery insulation and animal ethics and welfare

Intraoperative and postoperative insults are a crucial part of the animal experiment. Whether to maintain the insulation measures is directly related to the success or failure of the experiment, and also the scientific ethics and welfare of the experimental animals in the life science related research. The true embodiment of putting into practice is a manifestation of the social responsibility of animal love. Be kind to living animals and reduce the pain of animal death! ! !

Scientific value of animal surgery insulation

Responsible scientists know that good science and good animal care go hand in hand, and would not tolerate cruel or inhumane treatment of any laboratory animal.

------The US Animal Welfare Act

The US Animal Welfare Act affirmed that “responsible scientists know that good science and good animals are complementary, and we cannot tolerate killing or inhuman treatment of any experimental animal.”

Guarantee the accuracy of animal experiment results: scientific research is better, results are credible, more objective and true

Animal surgery hypothermia

Why do you need to keep your surgical animals warm?

1. Damage to the body's immune function, reduce skin blood flow and oxygen supply, increase wound infection rate

2. Reduce blood circulation and blood parameters, leading to coagulation, which is very unfavorable for monitoring and measuring blood or blood flow related indicators, such as measuring blood flow, blood pressure, etc.

3. Reduce the metabolism rate of drugs in the body tissues, affecting the body's metabolism

4. Prolonging the recovery time of anesthesia may significantly increase animal mortality

5. Cause other diseases, such as cardiovascular complications

6. Unable to get real or near real experimental data

7. More.........

Common causes of hypothermia in animal surgery

• 1. The role of anesthetics: anesthesia causes dilatation of blood vessels, inhibition of body temperature regulation, resulting in decreased body temperature

• 2. The low temperature environment of the operating room, especially the experimental environment of the common animal room

• 3. The "cold" material of the operating table, such as stainless steel, resin countertops

• 4. Long-term drug injection: long-term input of liquid with isothermal environment, causing "cold dilution" of animal body fluids, resulting in decreased body temperature of animals

• 5. The use of skin disinfectants, especially large areas of naked skin, resulting in heat loss in the body

• Prolonged surgery

• 6. Larger traumatic thoracotomy and open surgery, resulting in more heat dissipation

• 7. Animal age, disease factors, such as malnutrition, tumor model surgery

• Others.........

Common measures for animal surgery insulation

Solution 1

Solution 2

Standard operation of animal surgical insulation

Intraoperative

1. If the electric blanket insulation method is used, the electric blanket should not be placed directly on the operating table of "cold" material such as stainless steel or resin. The heat transfer of these materials will cause the electric blanket to heat slowly or even not to heat up to the expected temperature;
2. Except for the surgical site, other parts should not be exposed as much as possible, and can be covered with a cloth towel;
3. If the liquid or drug is injected and the experiment time is long, if necessary, the liquid input into the animal body can be preheated at the same time;
4. Surgical operation is proficient and reduces the operation time;
5. Pay attention to body temperature monitoring.

Postoperative

• Continue to place the animal on the insulation blanket or the insulation table until the animal is restored.

Animal surgery anesthesia, insulation complete program

Solution 1

This set of programs integrates inhalation anesthesia, stereotactic positioning and animal surgery insulation. It is a standard configuration for neuroscience related research in small animals such as mice and rats. The main application areas are:

1. Light inheritance

2. 2. Neuroelectrophysiology

3. 3. Calcium imaging

4. 4. Microdialysis

5. 5. Brain & Spinal Cord Injury

6. 6. Intracranial administration

7. And more........

Solution 2

This set of programs integrates the functions of inhalation anesthesia, animal body fixation and surgical insulation. It is a standard configuration for common experiments in small animals such as mice and rats. The main application areas are:

1. 1. Animal anatomy, separation

2. 2. Modeling of cerebral infarction, myocardial infarction, etc.

3. 3. Heart, tail vein, vein and other ischemia

4. 4. Internal jugular vein and tail vein administration

5. 5. Live imaging of animals

6. And more........

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