Sleep changes or early indicators of Alzheimer's disease

January 30, 2024

Sleep changes or early indicators of Alzheimer's disease

January 17, 2019 Source: Science and Technology Daily

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In patients with Alzheimer's disease (AD), β-amyloid plaques and tau tangles accumulate in the brain long before clinical symptoms appear. Therefore, early intervention is critical to slowing neurodegenerative diseases and disease progression, but scientists need to find reliable early markers. Researchers at the University of Washington in St. Louis, Brandon Lucy, analyzed sleep patterns in elderly cognitively normal subjects and found non-rapid eye movement (NREM) and tau pathology and several brain regions of beta-amyloid deposits. Negative correlation. Studies have shown that changes in non-REM sleep may be an early indicator of the pathology of Alzheimer's disease and suggest that non-invasive sleep analysis may help monitor patients at risk for Alzheimer's disease.

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