There are new ways to cultivate human cells for skin transplantation
The British "Nature·Communication" magazine published a new medical breakthrough on the 30th: Duke-Singapore National University Medical School successfully developed a new method of artificial cultivation of human cells, which can generate the tissue needed for skin transplantation, and is expected to be applied to the treatment of human body. Severe burns and other skin problems. Self-transplantation is a common method for treating skin defects caused by trauma, burns and other factors. In recent years, skin grafting has made tremendous progress, and the medical profession has been able to repair up to 90% of the epidermis of patients with severe skin wounds or burns. This type of treatment requires first collecting skin cells from the patient, culturing the cells into a large piece of tissue in vitro, and then transplanting them onto the wound surface. However, mouse cells are often required to support tissue growth in cell culture media. But this mixture of human/mouse cells exposes patients to the risk of large-scale infections and adverse immune responses. This time, Duke-University of Singapore medical school researcher Carl Tregvarson and colleagues found that two specific variants of laminin commonly found in humans can support the growth of skin cells in a similar manner. Laminin is a non-collagen sugar, also known as lamellar, which constitutes the interstitial cells. Its biological function is the medium in which cells adhere to the matrix and binds to various basement membrane components to regulate cell growth and differentiation. The results of this study have enabled researchers to successfully establish animal-free human cell culture systems for skin transplantation without using mouse cells. The research team subsequently confirmed that the skin tissue obtained by this method has been successfully transplanted into mice. (Reporter Zhang Mengran) Head Immobilizer,Head Blocks,Emergency Head Immobilizer Supplier Head Immobilizer,Head Blocks,Emergency Head Immobilizer,Child Head Holder,Assembled Head Immobilizer Luck Medical Consumables Co.,LIMITED , https://www.luckmedical.com