Epstein-Barr virus may induce breast cancer
Epstein-Barr virus may induce breast cancer August 03, 2016 Source: Bio Valley Recently, a research report published in the international magazine EBioMedicine , researchers from the Beth Israel Deaconess Medical Center and Harvard Medical School found that the infection of Epstein-Barr virus (human herpesvirus type 4) may increase some The risk of breast cancer in women, related research or screening for breast cancer and effective prevention will help. Epstein-Barr virus is one of the eight viruses that infect the human herpesvirus family, and it is also the most common type of virus that causes infectious mononucleosis; more than 90% of the world's population carry EBs. The virus, and most individuals have not experienced the effects of infection. However, Epstein-Barr virus is thought to be associated with a variety of cancers in specific individuals, including Burkitt's lymphoma, lymphogranulomatosis, nasopharyngeal carcinoma, gastric adenocarcinoma, and leiomyosarcoma; in addition, many studies have reported EB virus infection and breast cancer. Cancer-related, but the researchers did not clarify the specific role and role of Epstein-Barr virus in the development and progression of breast cancer. In this paper, the researchers cultured mammary gland cells called primary mammary epithelial cells (MECs) in the presence of Epstein-Barr virus, and found that the virus can bind to the CD21 receptor on the surface of normal breast cells to cause infection, Epstein-Barr virus The infection causes the cells of the breast cells to exhibit the characteristics of stem cells to continuously divide and multiply; when primary mammary epithelial cells are implanted into the mouse body, EB virus infection cooperates with specific oncogenic proteins to accelerate the occurrence of breast cancer. The investigators analyzed the genetics associated with high-grade, estrogen receptor-negative breast cancer, a malignant breast cancer, when analyzing genes from primary breast epithelial cells infected with Epstein-Barr virus. Researcher Professor Wulf pointed out that we believe that if young women are infected with EBV in their adolescents or later, their body's mammary epithelial cells will be exposed to the virus and infected; for most individuals, EB virus infection is not It will cause long-term consequences, but in some individuals, it will cause changes in the metabolism of mammary epithelial cells and the production of "genetic scars". Although it is only a slight change, it may promote the body's mammary gland in a few decades. The occurrence of cancer. This study reveals that Epstein-Barr virus-induced breast cancer seems to be reasonable, and Epstein-Barr virus promotes cancer by inducing malignant transformation of primary mammary epithelial cells, and the results of the study may protect the body from the development of vaccines against Epstein-Barr virus. It provides new hopes and clues for infection and inhibition of late-stage and Epstein-Barr virus-associated carcinogenesis. Sterile Garments,Medical Protective Garments,Surgical Protective Clothing,Non Woven Protective Clothing Taizhou huangyan Yiman industry & trade limited , https://www.yimancoverall.com