These drugs are most likely to pose health risks after abuse

[ China Pharmaceutical Network Health and Wellness ] France's "Prescription" magazine recently released a "blacklist" of drugs. The list said that in France, after 91 drugs abuse, the health risks are most likely to occur. The use of medicines is globally connected. This special report for this expert, combined with the situation in China, summed up some drugs that are most prone to health risks after abuse.

(These drugs are most likely to cause health risks after abuse. Image Source: Baidu Pictures)
Antibacterial drugs. The antibacterial drugs listed in the blacklist are mainly quinolones such as moxifloxacin. Wu Yubo, director of the Department of Clinical Pharmacy, the Fourth Affiliated Hospital of Harbin Medical University, told the Life Times reporter that many people in their lives have a cold or diarrhea, and they use antibiotics to solve the problem. This is wrong. Generally, only colds, diarrhea, etc. caused by bacterial infections are effective. Abuse and overuse of antibacterial drugs can also cause various adverse consequences, such as inducing bacterial resistance, causing double infection, and damage to human organs. Studies have shown that children's abuse of quinolones can damage the cartilage of weight-bearing joints and affect bone growth. The instructions for quinolone drugs in China will also basically state "disabled under 18 years old". Therefore, antibacterial drugs must be eaten after the doctor has made a clear diagnosis, and do not blindly use it.
Antiallergic drugs. "The tacrolimus and chlorpheniramine mentioned in the list are relatively common allergic drugs," Wu Yubo said. "They are mainly used for urticaria, allergic rhinitis, allergic dermatitis and other diseases." Will handle it by itself. However, in general, it is best not to take more than one month of continuous administration of the same anti-allergic drugs, otherwise it may cause drug resistance and its toxic effects will “accumulate”. Therefore, if you take more than one month, you need to switch to another type of medicine or use it if necessary, instead of regular regular medication. Patients with acute joint pain, high fever, and bronchial asthma should seek medical advice directly. Do not take the medicine yourself. In addition, antihistamines such as chlorpheniramine can cause side effects such as arrhythmia and central inhibition, and abuse can increase the incidence of such side effects. In particular, people who need to drive or work at height should choose anti-allergic drugs that do not have central inhibition or lighter to avoid accidents.
painkiller. Where is the pain, many people will buy ibuprofen, aceclofenac and other non-steroidal anti-inflammatory drugs to ease. However, it should be reminded that long-term use of the drug can cause high blood pressure or aggravate the symptoms of hypertensive patients. The application should monitor blood pressure regularly, and go to the hospital every 3 months to adjust the dose or type according to the doctor's advice. In general, to determine the efficacy of painkillers, whether it is effective within 3 days, so if the symptoms have not been alleviated within 3 days, you should seek medical advice as soon as possible to avoid delay or aggravate the condition. Moreover, the drug has a dose "ceiling effect", that is, when the drug reaches a certain dose, the analgesic effect does not increase with the dose. It should also be noted that such drugs can alleviate moderate pain such as toothache, migraine, neuralgia, etc., and are almost ineffective for traumatic severe pain and cramps caused by visceral smooth muscle spasm.
Antitussives. The list mentioned a drug called compound forcodine, Wu Yubo told reporters that it is a central antitussive, consisting of folfine, pseudoephedrine hydrochloride and so on. However, it should be noted that if you take too much intake, it may cause adverse reactions such as lethargy and vomiting, especially for children. Therefore, the dosage of the drug is best determined by the doctor. Because of the inclusion of pseudoephedrine hydrochloride, patients with hypertension and coronary heart disease should be used with caution. In addition, Wu Yubo said that in China, many people's antitussives are used too quickly. In fact, cough is a beneficial protective reflex that promotes the elimination of sputum and the removal of foreign bodies in the respiratory tract. If the cough medicine is applied too early, it will inhibit the cough reaction and is not conducive to the discharge of sputum. Retention of sputum in the respiratory tract can affect breathing, cause chest tightness, difficulty breathing, etc., and may also induce lung infection. Finally, use cough medicine carefully before going to bed. In general, unless the cough is severe and frequent, which seriously affects sleep, it is not recommended to take central cough medicine before going to bed.
Antiemetic. Affected by advertisements such as "indigestion, using morphine", many patients regard morphine as a "savior" for the stomach. To alleviate discomfort, patients may take large doses or take it several times a day. Wu Yubo reminded that the domperidone (morphine) in the list is often used as a digestive drug, and it can be eaten as long as the stomach is uncomfortable. However, the European Medicines Agency issued a statement saying that domperidone is recommended for treatment only when patients have nausea and vomiting. It is not recommended to relieve symptoms such as bloating and heartburn. Moreover, recent studies have found that with the increase in the dose and duration of treatment, it may significantly increase the risk of a series of cardiac side effects, including QT interval prolongation and arrhythmia. Therefore, as a Class A over-the-counter drug, morphine is to be taken as short as possible (preferably no more than 1 week), as a small dose, and strictly according to the doctor's advice. Patients with heart disease should introduce their medical history to the doctor before going to prescribe the medicine, and let the doctor assess whether he can take the medicine.
laxative. "Constipation is not a disease, it can't be solved." There is also a drug for the treatment of constipation Pluca. Wu Yubo said that from the clinical point of view, many patients in China will abuse laxatives. Especially women, afraid of constipation, let the toxins accumulate in the intestines, make the face long-spotted, and use laxatives for constipation. Although laxatives can alleviate constipation, long-term use may damage the intestinal wall nerves and weaken intestinal function. Laxatives make the intestines of patients with constipation passively squirm under the stimulation of drugs, overload work, once the drug is stopped, the intestines of the labor will quickly stop, which will increase constipation and may also cause drug dependence. Therefore, patients with constipation are advised to improve by drinking water, exercise, etc., and then consult a doctor if necessary.

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